| ncRNA name | NRD-1 siRNA |
| ncRNA Category | siRNA |
| Disease name | proliferative vitreoretinopathy (PVR) |
| Species | Homo sapiens |
| Tissues/Cell_line | primary human retina pigment epithelial (HRPEpi) cells, human RPE cell line ARPE-19 |
| Methods | RT-PCR, immunoblot, Western blot, invasion assay, ELISA, siRNA transfection |
| Expression pattern | associated |
| Functional description | Gene silencing of NRD-1 in ARPE/EBV cells attenuated secretion of EMT-related cytokines and expression of ADAM10 and 17 and upregulated epithelial markers. |
| PubMed ID | 26244291 |
| Year | 2015 |
| Title | Regulation of ADAM10 and ADAM17 by Sorafenib Inhibits Epithelial-to-Mesenchymal Transition in Epstein-Barr Virus-Infected Retinal Pigment Epithelial Cells. |
| Drug-related ncRNA | NO |
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